Patient Perception of MS Symptoms Influences Functional Activity Difficulty
Study determines that the way patients with MS perceive their symptoms affects how difficult they report the ability to complete functional activities....
Study determines that the way patients with MS perceive their symptoms affects how difficult they report the ability to complete functional activities....
Vitamin D is a neuroactive steroid that carries out its biological functions through the vitamin D receptor (VDR). The VDR gene interacts with certain long noncoding RNAs (lncRNAs). The pres...
Cognitive behavioural therapies (CBTs) are a standard of care for treatment of many 'hidden symptoms' in people with MS (PwMS), such as stress, depression, and fatigue. However, these interv...
Patient-reported outcome measures (PROM) could provide clinicians with practical, cost-effective information on MS disease progression, according to findings published in Multiple Sclerosis ...
Increased global atrophy or pseudo-atrophy in the first year of treatment for MS is predictive of clinically definite MS (CDMS), while positive lesion activity in years 1 and 2 is related to...
The liver is a multifunctional organ that plays crucial roles in numerous physiological processes, such as production of bile and proteins for blood plasma, regulation of blood levels of ami...
This study aimed to explore the association between kidney function and the risk of relapse as well as prognosis in patients with aquaporin-4 (AQP4)-immunoglobulin G (IgG)-seropositive neuro...
Cognitive impairment is a hallmark of multiple sclerosis (MS) but is usually an under-recorded symptom of disease progression. Identifying the predictive signatures of cognitive decline in p...
Multiple sclerosis (MS) is a chronic and degrading autoimmune disorder mainly targeting the central nervous system, leading to progressive neurodegeneration, demyelination, and axonal damage...
The Latin American Brain Health Institute (BrainLat) has released a unique multimodal neuroimaging dataset of 780 participants from Latin American. The dataset includes 530 patients with neu...
Atrophied T2-lesion volume (aT2-LV) is an exploratory imaging marker in multiple sclerosis (MS) reflecting the volume of lesions subsumed into cerebrospinal fluid (CSF).To investigate the ef...
Participating in a group behavioral telehealth program may improve the ability of patients with MS to achieve clinically meaningful weight loss....
Performance outcome (PerfO) measures are based on tasks performed by patients in a controlled environment, making their meaningful interpretation challenging to establish. Co-calibrating Per...
Researchers observed an increased risk of sick leave in patients with MS several years before clinical onset of the disease....
Results of a registry study confirmed that early intensive treatment enhances long-term clinical outcomes by minimizing the accumulation of neurological damage. ...
The onset of MS-related progressive brain tissue loss (PBTL) precedes clinical disease onset by 5 to 6 years. ...
Fenebrutinib penetrates cerebrospinal fluid at sufficient enough levels to reduce activation of B-cells and microglia in vitro....
Highly effective therapies as a first-line option in pediatric-onset MS results in sustained reduction of clinical and radiological disease activity over 5 years....
Younger patients with MS have more tissue destruction in white matter lesions but also a higher capacity for remyelination....
Multiple sclerosis (MS) is an autoimmune and neurodegenerative disease of the central nervous system (CNS) that is characterized by myelin damage, followed by axonal and ultimately neuronal ...
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